Curcumin Facts/Proper Dosage and interactions

May 14, 2021

For joint problems and other inflammatory, one of the most popular products recently being used is Curcumin. It is described as “the yellow pigment in the spice turmeric”, [i] and is grown mostly in South and South East Asia[ii].  The versatility of curcumin continues to be known, as more studies indicate its many benefits. Let’s discover what other things Curcumin can do and how it may help provide natural support for a number of health conditions.

Benefits and Effects.

  • Preclinical studies show that curcumin has “antioxidant, anti-inflammatory, anti-cancer, and neuroprotective activities”[iii] which can help address a range of conditions and diseases such as cancer, Alzheimer’s disease, depression, liver diseases, heart disease and high blood cholesterol[iv].
  • Curcumin’s anti-inflammatory properties helps relieve joint pains and enhance joint health[v]. It contains anti-inflammatory compounds, which include COX-2 inhibitors, that block the production of prostaglandins which are the reason for pain and swelling[vi].
  • Curcumin can help increase the production of anti-oxidants in the body.[vii]
  • Curcumin’s anti-cancer capability can affect the spread of tumors, according to research, through “regulation of transcription factors, inflammatory cytokines, growth factors, protein kinases and other enzymes”[viii]. Curcumin stops tumor growth by depriving tumors of blood supply[ix].
  • Curcumin has also been found to impact positively on memory and mood, as revealed in a study conducted by UCLA[x].
  • Curcumin is one of over 200 bio-active compounds in turmeric.[xi]
  • Curcumin can also help in digestion because of the “cholagogue properties” which stimulates the production of bile and regulate its flow[xii].

Dosage. There are various studies on the safe dosage levels of curcumin that are acceptable and safe, with minimal side effects[xiii] such as Curcumin containing 500mg of the active ingredient.

Interactions. To help absorb curcumin into the cells, it can be taken in tandem with aspirin or ibuprofen which enables its absorption 10 times faster[xiv].

Curcumin can also be taken with the following[xv]:

  • Other curcuminoids (Curcumin, Demethoxycurcumin, Bimethoxycurcumin, Cyclocurcumin)
  • Piperine (increases bioavailability)
  • Genistein and soy isoflavones (synergistic protection from prostate cancer)
  • Fish Oil, particularly DHA, for breast cancer prevention
  • Garcinol, from Garcinia Indica, for cancer prevention
  • A wide variety of chemotherapy pharmaceuticals

1 NutritionFacts.org. [n.d.] Curcumin. Retrieved from https://nutritionfacts.org/topics/curcumin/

2 Mandal, A. [2019, February]. What is Curcumin. Retrieved from https://www.news-medical.net/health/What-is-Curcumin.aspx

3 Global Curcumin Association. [n.d.] An Overview of Curcumin and Current Industry Trends. Retrieved from https://curcuminassociation.org/curcumin-resources/

4 Mandal. A. [2019, February]. Curcumin Health Effects. Retrieved from https://www.news-medical.net/health/Curcumin-Health-Effects.aspx

5 Patel, K. [2019, June]. Curcumin. Retrieved from https://examine.com/supplements/curcumin/

6 Dill, D. [2015, June]. How Herbs Work: Turmeric and Curcumin. Retrieved from https://www.naturalnewsblogs.com/herbs-work-turmeric-curcumin/

7 Patel, K. [2019, June]. Curcumin. Retrieved from https://examine.com/supplements/curcumin/

8 Mandal, A. [2019, February]. What is Curcumin. Retrieved from https://www.news-medical.net/health/What-is-Curcumin.aspx

9 Dill, D. [2015, June]. How Herbs Work: Turmeric and Curcumin. Retrieved from https://www.naturalnewsblogs.com/herbs-work-turmeric-curcumin/

10 Hopper, L. [2018, January]. Curcumin improves memory and mood, new UCLA study says. Retrieved from http://newsroom.ucla.edu/releases/curcumin-improves-memory-and-mood-new-ucla-study-says

11 Dill, D. [2015, June]. How Herbs Work: Turmeric and Curcumin. Retrieved from https://www.naturalnewsblogs.com/herbs-work-turmeric-curcumin/

12 Dill, D. [2015, June]. How Herbs Work: Turmeric and Curcumin. Retrieved from https://www.naturalnewsblogs.com/herbs-work-turmeric-curcumin/

13 Shruti. [n.d.] Curcumin: Side Effects and Precautions. Retrieved from https://www.turmericforhealth.com/curcumin-benefits-and-dosage/curcumin-side-effects-and-precautions-must-read

14  Williams, A. [2019, June]. Drug Interactions with Curcumin? Retrieved from https://turmericsgold.com/safety/drug-interactions-with-curcumin/

15  Patel, K. [2019, June]. Curcumin. Retrieved from https://examine.com/supplements/curcumin/

This article was originally posted in Pharexmedics.com